Credelio Quattro Chewable Tablets for Dogs, 12.1-25 lbs, 6 Chewables (6-mos. supply)

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About This Item

Details

Credelio Quattro (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) is the broadest parasite protection of its kind covering 6 types of parasites in one chewable tablet. It protects against ticks, fleas, heartworm disease and the three intestinal worms that can be passed to humans: tapeworms, roundworms and hookworms. Credelio Quattro is effective and works fast where it counts. It kills >99% of fleas within 8 hours of administration and remains effective for an entire month. This FDA-approved medication delivers all the protection your dog needs in a convenient monthly chewable. It uses four powerful ingredients to provide the broadest protection that lasts all month long by covering 6 types of parasites. Credelio Quattro comes in a tasty, easy-to-give chewable that's also meat allergy friendly. In fact, Credelio Quattro was accepted by nearly 9 out of 10 dogs.

We directly source prescription medications from manufacturers and wholesale distributors registered with the FDA and licensed by applicable state boards. Guaranteed genuine, and where applicable, backed by the manufacturer.

Ingredients

Instructions

FAQ

Get 6-in-1 Parasite Protection

Introducing Credelio Quattro (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) for dogs, a prescription medication that protects your dog from common parasites. Unlike other chewables, Credellio Quattro protects against 6 types of parasites, including ticks, fleas, heartworm disease and three intestinal worms that can be passed to humans – 3 species of tapeworms, roundworms and hookworms.

Protection in a Tasty Chewable

Credelio Quattro combines convenience with flavor. A beef-flavored, once-monthly tablet that makes it easy to administer. Enjoy peace of mind knowing your dog’s protection is effective and easy to give.

The Power of Four

Credelio Quattro features four tried and true active ingredients designed to combat parasites effectively. With lotilaner, moxidectin, pyrantel and praziquantel, this advanced formula provides your pet with the broadest parasite protection of its kind based on label comparison of the number of parasite types covered.

Shown To Be Safe for Dogs and Puppies

Use Credelio Quattro to help protect your dog proactively before problems happen. This preventive treatment is shown to be safe for puppies as young as 8 weeks old and weighing at least 3.3 lbs.

About Credelio Quattro

Prescription only. Ask your veterinarian if Credelio Quattro is right for your dog.

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Indications

Credelio Quattro is indicated for the prevention of heartworm disease and the treatment and control of roundworm, hookworm, and tapeworm infections. Credelio Quattro kills adult fleas and is indicated for the treatment and prevention of flea infestations and the treatment and control of tick infestations for 1 month in dogs and puppies 8 weeks of age and older and weighing 3.3 pounds or greater.

Important Safety Information

Lotilaner, an ingredient in Credelio Quattro, belongs to the isoxazoline class and has been associated with neurologic adverse reactions like tremors, ataxia, and seizures even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infections before Credelio Quattro administration as it is not effective against adult D. immitis. The safe use in breeding, pregnant, or lactating dogs has not been evaluated. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. For complete safety information, please see the Credelio Quattro product label or ask your veterinarian.

4.6
Rated 4.6 out of 5 stars
135 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

82% Positive

Effectiveness

80% Positive

Ingredients

79% Positive

Long-Term Benefits

75% Positive

50 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 1 out of 5 stars
By Kathleen on Oct 7, 2025

Will not purchase again

Dog shakes and acts drunk after taking .i have 2 pugs ,12 and 2 years old. Both dogs experienced the same symptoms drunk and shaky , wobbly . I think it’s too

Dog shakes and acts drunk after taking .i have 2 pugs ,12 and 2 years old. Both dogs experienced the same symptoms drunk and shaky , wobbly . I think it’s too strong for my pugs . So I will go back to just heartworm and flee tick separately instead of all in one.


Rated 5 out of 5 stars
By Angella on Sep 29, 2025

Ease of ordering and no fleas! Whoop whoop!!

So easy to do authorship and not have to think of anything. Credelio is the best. Not even close to anything else. Love it and my pups love not having to have fleas

So easy to do authorship and not have to think of anything. Credelio is the best. Not even close to anything else. Love it and my pups love not having to have fleas. I used another medicine and they had fleas for the first time. Not anymore with Credelio.


Rated 1 out of 5 stars
By Stacy on Oct 3, 2025

Diarrhea

After receiving the tablet , my dog within eight hours and for the two days had diarrhea! We have narrowed it down to this...would like a refund.

After receiving the tablet , my dog within eight hours and for the two days had diarrhea! We have narrowed it down to this...would like a refund.


Rated 4 out of 5 stars
By Daniella on Oct 6, 2025

It was okay

I really felt that it took a week and a half to really kick in and then even at that they were still itching more than usual.

I really felt that it took a week and a half to really kick in and then even at that they were still itching more than usual.


Rated 5 out of 5 stars
By Sandra on Sep 26, 2025

Quickness

I was impressed with the speed of Chewy obtaining the Rx from my vet. Also the quickness of you sending and my receiving the order.

I was impressed with the speed of Chewy obtaining the Rx from my vet. Also the quickness of you sending and my receiving the order.


Rated 5 out of 5 stars
By Tammi on Jul 21, 2025

Perfect

I live in an area where ticks are a very big problem. I was using Simperica Trio but came across this and it killed more and was cheaper. Olee has had no issues

I live in an area where ticks are a very big problem. I was using Simperica Trio but came across this and it killed more and was cheaper. Olee has had no issues taking this medicine and I have yet to find one tick on him since starting this medication.


Rated 5 out of 5 stars
By Mike on Sep 12, 2025

4 in 1 flea, tick, and worm prevention

4 treatments in 1 to keep our pup healthy and pest free. She gobbles it up like a treat and tolerates it well with no apparent issues.

4 treatments in 1 to keep our pup healthy and pest free. She gobbles it up like a treat and tolerates it well with no apparent issues.


Rated 5 out of 5 stars
By Lori on Sep 16, 2025

Everything in One!

One tablet once a month protects my little guy from all the dangers! I appreciate how much this one tablet covers!

One tablet once a month protects my little guy from all the dangers! I appreciate how much this one tablet covers!


Rated 5 out of 5 stars
By Hannah on Jun 3, 2025

Palatable and Convenient

I was looking for a chewable tablet for my dogs that had pretty decent coverage for fleas, ticks, and worms. Credelio Quattro checked that box and the dogs take

I was looking for a chewable tablet for my dogs that had pretty decent coverage for fleas, ticks, and worms. Credelio Quattro checked that box and the dogs take this a lot easier than two separate pills for flea/tick and heartworm. No off side effects and we haven't seen any unwanted hitchhikers.


Rated 5 out of 5 stars
By Ruth on Sep 29, 2025

Ease of ordering

This will be delivered every month when it’s time for the pill. One pill.

This will be delivered every month when it’s time for the pill. One pill.